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CBG – Here’s Why You Should Care

CBG

CBG – the cannabis plant is home to several different types of compounds and by now, you have probably heard of the most famous ones like THC or CBD but there is actually so much more to the cannabis plant than those two ingredients – including CBG

The cannabis plant is made of several different things like flavonoids, terpenes, and of course cannabinoids. But do you know where all these cannabinoids come from? They are actually converted from one of the compounds in the plant: CBG.

So, what is CBG? 

CBG or cannabigerol is considered to be the precursor to all other cannabinoids. It is known as the building blocks which other cannabinoids are created from and is usually quite rare to come across. Of the 100+ compounds in cannabis, Cannabigerol is slowly stealing the spotlight in the medicinal world for its promising therapeutic and medicinal potential.

Want to learn more about this elusive cannabinoid? Let us walk you through the basics of CBG and how you can benefit from this compound.

The Basics of CBG

CBG

Cannabigerol or CBG is a phytocannabinoid that operates like a stem cell to other cannabinoids. It can be used to create any of the other main types of cannabinoids or left to be isolated for its own set of unique characteristics. That said, CBG is the precursor of the three main lines of cannabinoids: THCA, CBDA, and CBCA.

In the early stages of the cannabis plant’s life cycle, it produces high levels of CBGA which then get converted to CBG and then either to THCA, CBDA, or CBCA depending on the plant’s genetic profile. From there, through decarboxylation, the THCA gets converted to THC, the CBDA to CBD, and the CBCA to CBC.

Unfortunately, CBG is still somewhat of a mystery to scientists as it has only been recently that they have started looking deeper into the cannabinoid. In fact, research is still in its infancy, and clinical trials still need to be done in order to determine and figure out the nuances of CBG.

However, even though research is still in its infancy, cannabigerol has been showing a vast array of beneficial medicinal properties not found in other cannabinoids. Even further, the added ability to initiate the entourage effect could mean that CBG could be beneficial both as an isolate or even when used in a mixture of other cannabinoids. Of course, more testing is required to come to a solid conclusion.

So far, in animal experiments, CBG has shown promise in treating issues like Glaucoma, Inflammatory Bowel Disease, and various types of cancers.

How Does CBG Compare to CBD?

Both CBG and CBD are non-psychoactive cannabinoids that are known to act upon the CB1 and CB2 receptors in our Endocannabinoid System

The human body’s Endocannabinoid System works to regulate several functions and keep the body in a state of homeostasis. That said, both cannabinoids have some similarities in that they both interact with the same receptors and both have anti-inflammatory effects.

As it currently stands, the main difference between CBG and CBD is that CBD elicits its effects purely through indirect interaction with our endocannabinoid system, while cannabigerol is known to interact directly with the CB1 and CB2 receptors to employ its effects.

It is also important to note that CBD also carries a much greater body of research when compared to CBG, as CBG is still a relatively new area of study.

What Are Its Potential Medical Benefits?

cbg benefits

Even though studies on CBG are limited, they do exist and have pointed out the immense potential for CBG. Here are some of the ways CBG could be applied in the future.

Inflammation

A common benefit among other cannabinoids like CBD, CBG has been shown to also help fight signs of inflammation. A controlled study involving mice suggested that cannabigerol was effective at decreasing the total amount of inflammation associated with Inflammatory Bowel Disease.

Glaucoma

Interestingly, glaucoma, which is heavily associated with increased intraocular eye pressure and blindness seems to be alleviated by CBG. 

CBG has shown that it is effective in relieving intraocular eye pressure to a significant degree, alleviating the discomfort felt by those with Glaucoma, and potentially helping to decrease further progression of the disease.

Cancer

Cannabigerol has shown great potential in fighting cancer and tumors. Research has found that CBG was effective at blocking the receptors responsible for the proliferation of cancer cells

Not only that, but CBG may be able to penetrate the membranes of cancer cells in ways that CBGA, its acidic form cannot. A particular study on mice showed CBGs efficacy in controlling and containing colorectal cancer cells, helping to slow the growth of cancer. 

Expect to see more research being conducted behind the mechanisms of CBG as it could be a future form of treatment for a variety of cancers including digestive system cancer, brain cancer, and breast cancer.

Appetite Stimulant

Much like THC, CBG shows signs of it being an effective appetite stimulant. More specifically, in a recent study involving rats, cannabigerol was able to evoke senses of hunger in pre-satiated rats, making them eat more food at each meal at a much higher frequency, without the impairment of any psychoactive effects. 

More importantly, CBG’s appetite-stimulating properties may be able to provide some aid to those suffering from cachexia, a muscle-wasting disorder prevalent in the later stages of cancer.

The Cons of CBG

With all these positives about this new cannabinoid, there are some drawbacks to it. At the moment, CBG is incredibly expensive to produce and isolate. As mentioned before, it is only found in trace amounts in most commercial plants, meaning a large amount of biomass would be required to produce even a small amount.

Creating genetically pure CBG strains is also a relatively new way, as with current crops, growers can either wait until it’s time to harvest the hemp plant or prematurely cultivate their crops for CBG before it gets converted into other cannabinoids.

It’s important to note that cannabis plants can also produce only a finite number of cannabinoids, and most crops have been geared towards producing either high levels of THC or CBD, with little room for CBG. 

When it comes to cannabinoid composition growers cannot simply have an abundance of each one, they must pick one or the other.

Final Thoughts

You’ve made it to the end and by this time you should have a basic understanding of CBG and the potential benefits it may offer. So far, CBG has shown great potential in treating glaucoma and cancer, fighting signs of inflammation and even acting as an effective appetite stimulant.

While it may offer several potential medicinal benefits, it is also very expensive to produce and isolate, so it would take some time before the research about this unique cannabinoid becomes more solid. 

As research progresses with CBG, we will do our best to keep you informed with the most current information on cannabigerol and the medicinal value it can provide. Until next time!

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